Unrestricted Access

Connection note

The free TOXNET database, maintained by the National Library of Medicine, will be retiring on December 16, 2019 (
The content from TOXNET will be moved into several other NLM databases, including PubMed, PubChem, and NCBI Bookshelf. A list of which content will be moved to which database is available at


TOXNET, is a cluster of databases covering toxicology, hazardous chemicals, environmental health and related areas. It is managed by the Toxicology and Environmental Health Information Program (TEHIP) in the Division of Specialized Information Services (SIS) of the National Library of Medicine (NLM). TOXNET provides free access to and easy searching of a number of toxicology databases including: HSDB (R) (Hazardous Substances Data Bank), IRIS (Integrated Risk Information System), Carcinogenic Potency Database, CCRIS (Chemical Carcinogenesis Research Information System), GENE-TOX (Genetic Toxicology), Tox Town, Household Products Database, Haz-Map (R), TOXMAP, and LactMed (Drugs and Lactation). TOXNET also includes toxicology literature and chemical identification databases: TOXLINE, DART (R)/ETIC (Development and Reproductive Toxicology/Environmental Teratology Information Center), Toxics Release Inventory (TRI) and ChemIDplus.

Dates covered

Varies among databases; TOXLINE Core, TOXLINE Special and the DART database contain bibliographic citations dating from 1965 to present, however it is possible you may retrieve a few citations dating as far back as the 1940s.

Updating frequency

TOXNET databases are updated when new information becomes available.


Books, encyclopedias, handbooks, journals, government publications, technical reports, and also archival collections that are no longer being updated: EMIC (Environmental Mutagen Information Center file), NIOSHTIC (NIOSH), Poisonous Plants Bibliography (PPIB) and others.

Type of coverage

Bibliographic citations with abstracts, carcinogenicity studies, chemical dictionary, chemical records with structure and physical data, mutagenicity studies, tumor inhibition and tumor promotion studies, etc.

Print counterpart or
related resources

None. TOXNET is a gateway to a variety of electronic resources.

Producer/content provider

NLM's Toxicology and Environmental Health Information Program, part of the division of Specialized Information Services

Vendor/electronic presentation provider

National Library of Medicine

Supplementary Subject(s)